Fig. 2

Knockdown of GRP78 suppresses proliferation and metastasis in ARO and FRO cells. a Western blotting analysis of GRP78 protein expression in ARO and FRO cells transfected with si-NC, si-GRP78-1 and si-GRP78-2. b CCK-8 proliferation assays were performed to determine the viability of siGRP78-transfected ARO and FRO cells. ∗∗p < 0.01. c Transwell assays were performed to assess the migration of siGRP78-transfected ARO and FRO cells. Bar graphs represent the average migration rate of ARO and AFO cells. ∗∗∗p < 0.001