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Fig. 3 | Cell & Bioscience

Fig. 3

From: Overexpression of pyruvate dehydrogenase phosphatase 1 promotes the progression of pancreatic adenocarcinoma by regulating energy-related AMPK/mTOR signaling

Fig. 3

PDP1 overexpression promoted PDAC growth in vivo. a PDP1 overexpression significantly increased the luciferase signal in the orthotopic tumors of PDAC in mice; b PDP1 overexpression increased the tumor size of the orthotopic PDAC model; c H&E staining suggested that more cells were undergoing mitotic proliferation in the PDP1-overexpressing tumors than the control tumors; d PDP1-overexpressing tumors expressed a higher level of PCNA than the control tumors. ***p < 0.001

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Cell & Bioscience

ISSN: 2045-3701

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