Fig. 8

The effects of AMPK on DOR-mediated autophagy in the OGD/R model. a Images of MDC staining of SH-SY5Y cells exposed to different treatments. b Quantitative analysis of MDC-positive vacuoles in cells (N = 30 per group). Scale bar = 10 μm. The values are shown as the mean ± SEM. Significant differences: the OGD/R group vs. the DADLE group and the naltrindole group (***p < 0.001), the DADLE group vs. the DADLE + naltrindole group, the DADLE + 3-MA group and the DADLE + compound C group (***p < 0.001) in b. DAD DADLE, Nal naltrindole