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Fig. 6 | Cell & Bioscience

Fig. 6

From: Ghrelin, a novel therapy, corrects cytokine and NF-κB-AKT-MAPK network and mitigates intestinal injury induced by combined radiation and skin-wound trauma

Fig. 6

Ghrelin therapy decreases cell apoptosis and caspase-3 activation in ileum. Animals were irradiated alone or followed by wounding. A Slides from ileum samples from day 15 were stained for apoptosis assessment. The representative slides for each group are presented. B The apoptotic cells per crypt were counted. C-E Ileum samples at different time points were collected for measuring caspase-3 activation (N = 6 per group). The data presented are mean ± sem. *p < 0.05 vs. Sham VEH group; ^p < 0.05 vs. respective VEH group. VEH vehicle, GHR Ghrelin, W wounding; RI: 9.5 Gy; CI: 9.5 Gy + wounding

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Cell & Bioscience

ISSN: 2045-3701

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