Table 4 Probable list of epigenetic biomarkers targeting all subtypes of breast cancer
From: A three layered histone epigenetics in breast cancer metastasis
S. no. | Biomarkers | Association with hormonal receptors | Breast cancer subtypes |
|---|---|---|---|
1. | APLF | TNBC | Basal |
2. | HJURP | ER−ve, PR−ve | Luminal A |
3. | MacroH2A.1 | TNBC HER-2 | Basal (more), Luminal (less) HER-2-enriched |
4. | ɣH2AX | TNBC HER2−ve HER2+ve | Basal, HER2 enriched Luminal A/B (less) Luminal B (less than TNBC) |
5. | H2Bub1 | ER+ve TNBC | Luminal A/B (more expression) Basal (less expression) |