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Table 4 Probable list of epigenetic biomarkers targeting all subtypes of breast cancer

From: A three layered histone epigenetics in breast cancer metastasis

S. no. Biomarkers Association with hormonal receptors Breast cancer subtypes
1. APLF TNBC Basal
2. HJURP ER−ve, PR−ve Luminal A
3. MacroH2A.1 TNBC
HER-2
Basal (more), Luminal (less)
HER-2-enriched
4. ɣH2AX TNBC
HER2−ve
HER2+ve
Basal, HER2 enriched
Luminal A/B (less)
Luminal B (less than TNBC)
5. H2Bub1 ER+ve
TNBC
Luminal A/B (more expression)
Basal (less expression)