Fig. 5

BTX-A downregulated P2X7 expression. a Immunofluorescence double-labeling of P2X7 and CD11b and b Western blot analysis of P2X7 protein level in rat L4–L6 spinal cord segments fourteen days after CCI induction in the groups of Sham, NP, BTX-A-10, and BTX-A-20. c Western blot analysis of P2X7 protein level in HAPI cells treated without or with BTX-A (0.1 nM) and LPS (100 ng/mL). ^**P < 0.01, vs. Sham; ^##P < 0.01, vs. NP; ^$$P < 0.01, vs. Ctrl; ^&&P < 0.01, vs. LPS