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Table 1 Experimental studies that investigated the role of piRNAs in breast cancer

From: PIWI-interacting RNAs: new biomarkers for diagnosis and treatment of breast cancer

PiRNA Function Type of breast cancer or its cell line Model Expression References
PiR-36712 Promotes cancer cell proliferation, invasion and migration Invasive breast ductal carcinoma In vitro and In vivo Underexpressed [79]
PiR-34736 Progression of cell cycle Invasive breast ductal carcinoma In vitro Underexpressed [82]
PiR-36249 Progression of cell cycle Invasive breast ductal carcinoma In vitro Underexpressed [82]
PiR-35407 Progression of cell cycle Invasive breast ductal carcinoma In vitro Underexpressed [82]
PiR-34377 Progression of cell cycle Invasive breast ductal carcinoma In vitro Underexpressed [82]
PiR-36318 Progression of cell cycle Invasive breast ductal carcinoma In vitro Underexpressed [82]
PiR-36026 Progression of cell cycle Invasive breast ductal carcinoma In vitro Overexpressed [82]
PiR-31106 Progression of cell cycle Invasive breast ductal carcinoma In vitro Overexpressed [82]
PiR-36743 Progression of cell cycle Invasive breast ductal carcinoma In vitro Overexpressed [82]
PiR-20582 Tumor marker Invasive breast ductal carcinoma In vitro Overexpressed [83]
PiR-4987 Lymph node positivity Invasive breast ductal carcinoma In vitro Overexpressed [83]
PiR-20365 Tumor marker Invasive breast ductal carcinoma In vitro Overexpressed [83]
PiR-20485 Tumor marker Invasive breast ductal carcinoma In vitro Overexpressed [83]
PiR-651 Tumor progression Bcap-37 cell line In vitro Overexpressed [39]
PiR-021285 Modulates
Breast cancer invasiveness
MCF7 breast cancer cell lines In vitro Overexpressed [78]
PiR-932 Promotes methylation of Latexin and form immune complexes Breast cancer stem cells(CSC) In vitro Overexpressed [85]