Fig. 1
From: PRL2 serves as a negative regulator in cell adaptation to oxidative stress
PRL2 negatively regulates oxidative stress induced cell death in vitro. a Relative cell viability of bone marrow cells from PRL2+/+, PRL2+/− and PRL2−/− mice was measured by the CCK-8 assay following oxidative stress induced by various concentrations of H2O2. b PRL2−/− MEFs were transfected with pRK5. 24 h after transfection, relative cell viability was measured by the CCK-8 assay following oxidative stress induced by various concentrations of H2O2. c The growth curves of 293T stable cell lines with or without PRL2 overexpression were measured by the CCK-8 assay and shown in the form of absorbance at 450 nm. d 293T stable cell lines with or without PRL2 were treated with various concentrations of H2O2. Relative cell viability was measured by the CCK-8 assay. Error bars represent the SEM. Statistics were performed on pooled data from 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.005