Potential microRNA-related targets in clearance pathways of amyloid-β: novel therapeutic approach for the treatment of Alzheimer’s disease

Table 2 MiRNAs and their downregulated mRNA targets in the autophagy cascade

MiRNA	Function	Gene	References
miR-144, miR-99b-5p, miR-199a-3p	Autophagy initiation	mTOR	[102,103,104]
miR-100		RAPTOR	[105]
miR-181b		mLST8	[106]
miR-375		DEPTOR	[107]
miR-25		ULK1	[108]
miR-26b		ULK2	[109]
miR-4459		ATG13	[110]
miR-224-3p		FIP200	[111]
miR-17-5p, miR-30a	Vesicle nucleation	BECN1	[112, 113]
miR-195, miR-152		ATG14	[114, 115]
miR-33a, miR-183		UVRAG	[116, 117]
miR-21		VPS34	[118]
miR-299-5p, miR-181a	Autophagosome elongation	ATG5	[119, 120]
miR-23b, miR-200b		ATG12	[121, 122]
miR-142-3p, miR-410		ATG16L1	[123, 124]
miR-188-3p, miR-17		ATG7	[125, 126]
miR-4458, miR-4667-5p, miR-4668-5p		ATG10	[127]
miR-34a		ATG4B	[128]
miR-155		ATG3	[129]
miR-204, miR-497		LC3-II	[130, 131]

ISSN: 2045-3701