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Fig. 7 | Cell & Bioscience

Fig. 7

From: Long noncoding RNA lnc-DILC stabilizes PTEN and suppresses clear cell renal cell carcinoma progression

Fig. 7

AKT signaling pathway involves in the suppressive effects of lnc-DILC. a The phosphorylation of AKT (p-AKT) was detected by western blot in ccRCC cells with lnc-DILC alteration. b The ACHN cells with lnc-DILC overexpression were transfected with PTEN siRNAs or treated with the pharmacological activator of AKT signaling (SC79), and then the cell proliferation was determined by CCK-8 assay. c The ACHN cells with lnc-DILC overexpression were transfected with PTEN siRNAs or treated with the pharmacological activator of AKT signaling (SC79), and then the cell migration and invasion was determined by Transwell assay. *p < 0.05, **p < 0.01, ***p < 0.001

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