Fig. 1
From: Physical exercise: bulking up neurogenesis in human adults
Known pathways in neurogenesis and exercise promoted neurological benefits. a Embryonic origin of mature granule neurons (GNs) originate from adult-dentate gyrus (DG) progenitors derived from common embryonic stem cells. DGs differentiate into quiescent radial-glia like type I neural progenitor cells (Type I QNPs), then type II intermediate neural progenitors (Type II INPs), then Type III INPs, which eventually differentiate into immature and mature granule neurons (GNs). The genes and proteins used to label each differentiation stage are shown in the circle of each progenitor stage; b known physical exercise-promoted enhancement and recovery of cognitive functions