Fig. 2From: DUSP8 phosphatase: structure, functions, expression regulation and the role in human diseasesThe primary structure of human DUSP8 and mouse DUSP8. The (a) human and (b) mouse DUSP8 comprise three major domains: Rhodanese domain (in blue), Tyrosine-protein phosphatase domain (in green), and Pro-rich domain (in red). C246 means Cys-246, the catalytic site of DUSP8. As active site, KIM kinase interaction motifBack to article page