Fig. 5
From: LncRNA MALAT1 promotes osteoarthritis by modulating miR-150-5p/AKT3 axis
MALAT1 knockdown promotes the ECM degradation of chondrocytes in OA. The protein expression levels of MMP-13, ADAMTS-5, collagen II and aggrecan detected by western blot after transfecting with si-MALAT1 and stimulating with IL-1β (10 ng/mL) for 24 h. β-actin was used as an internal control. si-NC: treated with si-MALAT1 scramble; Control: not treated with IL-1β. *P < 0.05