Table 9 Distribution and comparison of combined 5′/3′ haplotypes of MBL2 in cases and controls
Haplotypes (5′ → 3′) | No. (%) of controls | No. (%) of cases | Haplotype comparison | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total RVVI cases | Clinical categories of RVVI | RVVI vs controls | BV vs controls | VVC vs controls | MI vs controls | ||||||||
(n = 218) | (n = 218) | BV (n = 112) | VVC (n = 56) | MI (n = 50) | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
Common | |||||||||||||
5′H-10/3′H-2 | 24 (11.00) | 23 (10.55) | 9 (8.03) | 8 (14.2) | 6 (12.00) | 1 | 1 | 1 | 1 | ||||
5′H-5/3′H-1 | 12 (5.50) | 16 (7.33) | 9 (8.03) | 3 (5.35) | 4 (8.00) | 1.39 (0.54–3.56) | 0.492 | 2.00 (0.63–6.34) | 0.2395 | 0.75 (0.16–3.35) | 0.706 | 1.33 (0.31–5.64) | 0.695 |
5′H-3/3′H-3 | 15 (6.88) | 10 (4.58) | 4 (3.57) | 3 (5.35) | 3 (6.00) | 0.69 (0.26–1.86) | 0.469 | 0.71 (0.18–2.72) | 0.618 | 0.60 (0.13–2.62) | 0.497 | 0.80 (0.17–3.68) | 0.774 |
5′H-1/3′H-1 | 14 (6.42) | 10 (4.58) | 10 (8.92) | 0 (0.00) | 0 (0.00) | 0.74 (0.27–2.01) | 0.561 | 1.90 (0.62–5.81) | 0.257 | – | NA | – | NA |
5′H-9/3′H-1 | 15 (6.88) | 8 (3.66) | 4 (3.57) | 2 (3.57) | 2 (4.00) | 0.55 (0.19–1.56) | 0.265 | 0.71 (0.18–2.72) | 0.618 | 0.40 (0.07–2.14) | 0.284 | 0.53 (0.09–2.99) | 0.475 |
5′H-1/3′H-2 | 9 (4.12) | 11 (5.04) | 4 (3.57) | 5 (8.92 | 2 (4.00) | 1.27 (0.44–3.64) | 0.649 | 1.18 (0.29–4.83) | 0.812 | 1.66 (0.43–06.45) | 0.459 | 0.88 (0.15–5.24) | 0.896 |
5′H-35/3′H-3 | 4 (1.83) | 11 (5.04) | 5 (4.46) | 3 (5.35) | 3 (6.00) | 2.86 (0.79–10.31) | 0.106 | 3.33 (0.72–15.26) | 0.121 | 2.25 (0.41–12.28) | 0.349 | 3.00 (0.52–17.15) | 0.216 |
5′H-60/3′H-1 | 3 (1.37) | 11 (5.04) | 7 (6.25) | 3 (5.35) | 1 (2.00) | 3.82 (0.94–15.49) | 0.060 | 6.22 (1.31–29.44) | 0.021* | 3.00 (0.50–17.95) | 0.228 | 1.33 (0.11–15.20) | 0.816 |