Table 8 Distribution and comparison of 5′ block haplotypes of MBL2 in cases and controls
Haplotypes (5′ → 3′) | No. (%) of controls | No. (%) of cases | Haplotype comparison | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total RVVI cases | Clinical categories of RVVI | RVVI vs controls | BV vs controls | VVC vs controls | MI vs controls | ||||||||
(n = 406) | (n = 516) | BV (n = 194) | VVC (n = 124) | MI (n = 82) | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
Common | |||||||||||||
HTTAXGQB (5′H-1) | 52 (12.80) | 98 (18.99) | 33 (17.01) | 20 (16.12) | 16 (19.51) | 1 | 1 | 1 | 1 | ||||
HTTAYGQB (5′H-2) | 57 (14.03) | 50 (9.68) | 19 (9.79) | 16 (12.90) | 6 (7.31) | 0.46 (0.28–0.77) | 0.003* | 0.52 (0.26–1.03) | 0.062 | 0.72 (0.34–1.55) | 0.415 | 0.34 (0.12–0.94) | 0.03* |
LTTAXGQB (5′H-3) | 39 (9.60) | 65 (12.59) | 27 (13.91) | 17 (13.70) | 7 (8.53) | 0.88 (0.52–1.48) | 0.643 | 1.09 (0.56–2.10) | 0.795 | 1.13 (0.52–2.44) | 0.749 | 0.58 (0.21–1.55) | 0.281 |
LTTAYGPA (5′H-4) | 51 (12.56) | 51 (9.88) | 12 (6.18) | 14 (11.29) | 10 (12.19) | 0.53 (0.31–0.88) | 0.01* | 0.37 (0.17–0.79) | 0.01* | 0.71 (0.32–1.56) | 0.399 | 0.63 (0.26–1.53) | 0.315 |
LGCGYAPA (5′H-5) | 24 (5.91) | 64 (12.40) | 19 (9.79) | 14 (11.29) | 14 (17.07) | 1.41 (0.79–2.52) | 0.238 | 0.55 (0.28–1.09) | 0.089 | 1.51 (0.65–3.50) | 0.329 | 1.89 (0.79–4.50) | 0.147 |
HTTAYAPA (5′H-6) | 17 (4.18) | 26 (5.03) | 11 (5.67) | 6 (4.83) | 3 (3.65) | 0.81 (0.40–1.63) | 0.557 | 1.01 (0.42–2.44) | 0.965 | 0.91 (0.31–2.65) | 0.874 | 0.57 (0.14–2.21) | 0.419 |