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Table 8 Distribution and comparison of 5′ block haplotypes of MBL2 in cases and controls

From: Impact of SNPs interplay across the locus of MBL2, between MBL and Dectin-1 gene, on women’s risk of developing recurrent vulvovaginal infections

Haplotypes (5′  → 3′) No. (%) of controls No. (%) of cases Haplotype comparison
Total RVVI cases Clinical categories of RVVI RVVI vs controls BV vs controls VVC vs controls MI vs controls
(n = 406) (n = 516) BV (n = 194) VVC (n = 124) MI (n = 82) OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
Common
 HTTAXGQB (5′H-1) 52 (12.80) 98 (18.99) 33 (17.01) 20 (16.12) 16 (19.51) 1   1   1   1  
 HTTAYGQB (5′H-2) 57 (14.03) 50 (9.68) 19 (9.79) 16 (12.90) 6 (7.31) 0.46 (0.28–0.77) 0.003* 0.52 (0.26–1.03) 0.062 0.72 (0.34–1.55) 0.415 0.34 (0.12–0.94) 0.03*
 LTTAXGQB (5′H-3) 39 (9.60) 65 (12.59) 27 (13.91) 17 (13.70) 7 (8.53) 0.88 (0.52–1.48) 0.643 1.09 (0.56–2.10) 0.795 1.13 (0.52–2.44) 0.749 0.58 (0.21–1.55) 0.281
 LTTAYGPA (5′H-4) 51 (12.56) 51 (9.88) 12 (6.18) 14 (11.29) 10 (12.19) 0.53 (0.31–0.88) 0.01* 0.37 (0.17–0.79) 0.01* 0.71 (0.32–1.56) 0.399 0.63 (0.26–1.53) 0.315
 LGCGYAPA (5′H-5) 24 (5.91) 64 (12.40) 19 (9.79) 14 (11.29) 14 (17.07) 1.41 (0.79–2.52) 0.238 0.55 (0.28–1.09) 0.089 1.51 (0.65–3.50) 0.329 1.89 (0.79–4.50) 0.147
 HTTAYAPA (5′H-6) 17 (4.18) 26 (5.03) 11 (5.67) 6 (4.83) 3 (3.65) 0.81 (0.40–1.63) 0.557 1.01 (0.42–2.44) 0.965 0.91 (0.31–2.65) 0.874 0.57 (0.14–2.21) 0.419
  1. Global p-value for case/control haplotype association was 0.01
  2. * p ≤ 0.01