Skip to main content

Table 12 Multifactor dimensionality reduction (MDR) analysis for the identification of best gene–gene interaction models for RVVI cases and controls

From: Impact of SNPs interplay across the locus of MBL2, between MBL and Dectin-1 gene, on women’s risk of developing recurrent vulvovaginal infections

Models SNPs interaction Training balance accuracy Testing balance accuracy Cross validation consistency OR (95% CI) χ2 value p-value
1 MBL2.rs7096206 (Y/X) 0.637 0.637 10/10 3.25 (1.84–5.74) 17.15 < 0.0001*
2 MBL2.rs36014597, MBL2.rs7096206 (Y/X) 0.657 0.623 9/10 5.33 (2.71–10.50) 26.05 < 0.0001*
3 MBL2.rs7096206 (Y/X), MBL2.rs10824792, CLEC7A.rs3901533 0.702 0.637 5/10 5.73 (3.15–10.45) 35.10 < 0.0001*
  1. * Indicates significant at p ≤ 0.001