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Fig. 3 | Cell & Bioscience

Fig. 3

From: Cardioprotective effects of microRNA-18a on acute myocardial infarction by promoting cardiomyocyte autophagy and suppressing cellular senescence via brain derived neurotrophic factor

Fig. 3

Down-regulated miR-18a promotes the hypoxia-induced H9c2 cell autophagy by promoting BDNF expression. a The number of autophagosomes induced by hypoxia quantified by immunofluorescence (×400); b the protein expression of BDNF and autophagy-related proteins (Beclin1, LC3-II/I and p62) determined by western blot analysis. The data were measurement data and expressed as mean ± standard error. Comparison was conducted by one-way analysis of variance among multiple groups. Each experiment was repeated 3 times; *p < 0.05 vs. the NC group; #p < 0.05 vs. the miR-18a inhibitor group

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