Fig. 1
From: MFAP5 promotes basal-like breast cancer progression by activating the EMT program
MFAP5 regulated the proliferation, adhesion and migration of BT20 and HS578T cells. BT20 cells in mock, LV-vehicle, LV-MFAP5 groups and HS578T cells in mock, control shRNA, MFAP5 shRNA groups were cultured at different time as indicated and then the proliferation, adhesion and migration of cells were examined. a Overexpressed MFAP5 time-dependently increased the proliferation of BT20 cells. **P < 0.01 vs LV-vehicle. b Knockdown MFAP5 in HS578T cells by shRNA inhibited cell proliferation. **P < 0.01 vs control shRNA. c Compared with LV-vehicle group, overexpressing MFAP5 significantly promoted BT20 cells adhesion. **P < 0.01 vs LV-vehicle. d Knockdown MFAP5 in HS578T cells by shRNA inhibited cell adhesion. **P < 0.01 vs control shRNA. e The migration of BT20 cells in LV-MFAP5 group was increased compared with those in LV-vehicle group. **P < 0.01 vs LV-vehicle. f Knockdown MFAP5 in HS578T cells by shRNA inhibited cell motility compared with those in control shRNA group. **P < 0.01 vs control shRNA