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Fig. 2 | Cell & Bioscience

Fig. 2

From: All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity

Fig. 2

BMP2/7 (5 or 50 ng/ml) ± ATRA (1 µM) modulated osteoclast marker gene expression in RAW264.7 cell cultures. a Calcr, b Acp5, and c Ctsk expression in RAW264.7 cells at day 1, 4 and 7. Values are mean ± SD, from three independent experiments. Significant effect of the treatment *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n.s. no significant difference

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