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Fig. 1 | Cell & Bioscience

Fig. 1

From: All-trans retinoic-acid inhibits heterodimeric bone morphogenetic protein 2/7-stimulated osteoclastogenesis, and resorption activity

Fig. 1

ATRA (1 µM) inhibited osteoclast precursor cells proliferation in presence or absence of BMP2/7 (5 or 50 ng/ml). Results of cell proliferation assay in RAW264.7 cell cultures (a). Cytotoxicity assay in BMM cell cultures (b), and RAW264.7 cell cultures (c). Values are mean ± SD, from three independent experiments. Significant effect of ATRA and/or BMP2/7 treatment, ****p < 0.0001, n.s. no significant difference

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