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Fig. 7 | Cell & Bioscience

Fig. 7

From: Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy

Fig. 7

CCDC47 mRNA and protein expression is increased in hearts of DIO rats. a CCDC47 mRNA levels in the atrium is increased in DIO rats (n = 4) compared to lean rats (n = 5). b CCDC47 mRNA levels in the ventricle is increased in DIO rats (n = 5) compared to lean rats (n = 7). c Representative Western blot of protein levels of CCDC47 in atrium of lean (n = 5) and DIO rats (n = 5) (top panel) and quantification of immunoreactive bands normalized to β-actin (bottom panel). Each lane represents an individual animal. d Representative Western blot of protein levels of CCDC47 in ventricle of lean and DIO rats. Quantification of immunoreactive bands normalized to α-tubulin were obtained from ventricle of lean (n = 9) and DIO (n = 8) rats. Each lane represents an individual animal. Bar graphs indicate mean + standard error. *p < 0.05 compared to lean control rats; ***p < 0.001 compared to lean control rats; ns non-significant difference compared to lean control rats

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