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Fig. 5 | Cell & Bioscience

Fig. 5

From: Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy

Fig. 5

Characteristic phenotype of a diet-induced obesity (DIO) rat model of cardiac hypertrophy. a Male Wistar rats (4 weeks old) that were maintained on a high fat diet for 6 weigh more than control rats fed a lean diet. b Insulin levels of rats measured at 20 weeks. White bars represent lean rats (n = 7) and black bars represent DIO rats (n = 8). c Fat content from subcutaneous abdomen, retroperitoneal and mesenteric compartments is increased in DIO rats compared to lean rats. d Ratio of heart weight/brain weight is increased in DIO rats compared to control rats. Bar graphs indicate mean + standard error. *p < 0.05, ***p < 0.001 and ****p < 0.0001 compared to lean control rats

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