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Fig. 3 | Cell & Bioscience

Fig. 3

From: LncRNA KCNQ1OT1 promotes osteogenic differentiation to relieve osteolysis via Wnt/β-catenin activation

Fig. 3

Effect of KCNQ1OT1 in mMSCs stimulated with PMMA particles. a ALP activity in mMSCs transfected with pcDNA KCNQ1OT1 or pcDNA before the addition of PMMA particles. b The mRNA expression levels of Runx2, Osterix and OCN in mMSCs transfected with pcDNA KCNQ1OT1 or pcDNA before the addition of PMMA particles. c Osteoblastic differentiation in mMSCs transfected with pcDNA KCNQ1OT1 or pcDNA before the addition of PMMA particles assessed by ARS staining. d The relative expression levels of KCNQ1OT1 in mMSCs transfected with pcDNA KCNQ1OT1 or pcDNA. *P < 0.05 compared with pcDNA-transfected cells. *P < 0.05 compared with control group. &P < 0.05 compared with PMMA + pcDNA group

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