Fig. 3

a The MAPT-AS1 expression level was determined by qRT-PCR in MDA-MB-231 and MDA-MB-468 cells transfected with MAPT-AS1 vector or empty vector. GAPDH was used as control. b, c The MDA-MB-231 and MDA-MB-468 cells were transfected with MAPT-AS1 vector or empty vector for 48 h. The relative cell proliferation was measured using CCK-8 assays and colony-forming assays. d, e Transwell assays were used to measure the migration and invasion ability of the two cell lines transfected with MAPT-AS1 vector or empty vector. f, g The two cell lines transfected with MAPT-AS1 vector or empty vector were then treated with paclitaxel for 24 h before CCK-8 assays or apoptosis detection. The apoptosis rate were measured using flow cytometry assays