Fig. 5

Inhibitory effect from aspirin on the expression of TLR4 on colon cancer cells leaded to the downregulation of NF-κB. a–c Western blot was used to explore the IκB activation in C26 cells with or without LPS, aspirin and TLR4 siRNA. d–f EMT markers expression was examined by real-time PCR and western blot in C26 cells with BAY 11-7082 treatment. (***P < 0.001)