Fig. 7

Exogenous H2S down-regulated IRE 1α-XBP-1 pathway. a IRE 1α; b XBP-1. The graphs represent the optical density of the bands of phosphorylated IRE 1α normalized with the expression of total IRE 1α. The graphs represent the optical density of the bands of XBP-1 normalized with the expression of GAPDH signal. The expression levels in the control group were considered the basal levels, and the others are expressed as fold change from the control group. The fold change values represent the mean ± S.E.M. of three determinations. **p < 0.01 vs. control group; #p < 0.05, ##p < 0.01 vs. H/R group; &&p < 0.01 vs. PC group; $p < 0.05 vs. H/R + NaHS group