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Fig. 5 | Cell & Bioscience

Fig. 5

From: Stromal Senp1 promotes mouse early folliculogenesis by regulating BMP4 expression

Fig. 5

BMPR1b expression in developing oocytes was reduced in SENP1-smKO mice. Ovaries from WT and SENP-smKO mice were harvested at postnatal day 7. a Protein levels of BMP4 and receptors were determined by western blot with respective antibodies. Normalized protein levels (with GADPH) are presented as fold changes by taking WT group as 1.0. n = 3. b BMP4 and SM22α co-immunofluorescence staining of ovaries from WT and SENP-smKO mice. c BMP4 and BMPR2 co-immunofluorescence staining of ovaries from WT and SENP-smKO mice. d, e SM22α and BMPR1B or BMPR2 co-immunofluorescence staining of ovaries from WT and SENP-smKO mice at postnatal day 7. Scale bars 15 μm. OV ovary, OC oocyte, GC granulosa cell, SC stromal cell. Asterisks indicate the same oocyte in the merged panel

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