Fig. 3

ImKTx88 ameliorates the EAE-induced loss of the TJ proteins. a The relative gene expression of occludin, ZO-1 and claudin-5 in cerebellar white matter were measured by qRT-PCR (n = 8–12). b Protein levels of occludin, ZO-1 and claudin-5 were detected via western blot (n = 4). Band densities were normalized to GAPDH and quantified. Experiments were repeated in triplicate. Data represent the mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001