Fig. 3From: Microhomology-mediated end joining: new players join the teamDomain structures of Polθ and its distinct functions. Polθ contain a N-terminal helicase like domain, a long central domian and a C-terminal polymerase domain. Polymerase domain mediates MMEJ. ATPase activity of helicase like domain and Rad51 binding motif in the central domain contribute to HR suppressionBack to article page