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Table 2 Top 30 genes down-regulated in ZIKV infected hNPCs compared to controls

From: Bioinformatic analysis reveals the expression of unique transcriptomic signatures in Zika virus infected human neural stem cells

Gene symbol Entrez Gene name Log2 FC p-value
SIGLEC10 89790 Sialic acid binding Ig-like lectin 10 −3.60664 0.00005
CDC20B 166979 Cell division cycle 20 homolog B (S. cerevisiae) −3.44083 0.0002
OR51E2 81285 Olfactory receptor, family 51, subfamily E, member 2 −3.05742 0.0001
CCNO 10309 Cyclin O −3.00562 0.00005
SLCO4A1 28231 Solute carrier organic anion transporter family, member 4A1 −2.97508 0.0229
SGPP2 130367 Sphingosine-1-phosphate phosphatase 2 −2.69025 0.00035
RRM2 6241 Ribonucleotide reductase M2 −2.63783 0.00005
SFXN2 118980 Sideroflexin 2 −2.61672 0.00005
COLEC12 81035 Collectin sub-family member 12 −2.60458 0.00005
CHRNA1 1134 Cholinergic receptor, nicotinic, alpha 1 (muscle) −2.5688 0.00005
PRR22 163154 Proline rich 22 −2.54683 0.00045
DHFR 1719 Dihydrofolate reductase −2.53145 0.00005
MFI2 4241 Antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 −2.50748 0.00005
MAPK15 225689 Mitogen-activated protein kinase 15 −2.46203 0.00005
C21orf58 54058 Chromosome 21 open reading frame 58 −2.39697 0.00005
SPEF1 25876 Sperm flagellar 1 −2.39565 0.00005
GHRL 51738 Ghrelin/obestatin prepropeptide −2.35804 0.00805
ATG16L2 89849 Autophagy related 16-like 2 (S. cerevisiae) −2.34225 0.00005
CXCL14 9547 Chemokine (C-X-C motif) ligand 14 −2.33189 0.0015
SUSD2 56241 Sushi domain containing 2 −2.28898 0.00005
C6orf118 168090 Chromosome 6 open reading frame 118 −2.27987 0.00005
DLX6-AS1 285987 DLX6 antisense RNA 1 −2.26662 0.00005
ADAM28 10863 ADAM metallopeptidase domain 28 −2.25906 0.00005
NXPH2 11249 Neurexophilin 2 −2.22856 0.00005
AQP7P1 375719 Aquaporin 7 pseudogene 1 −2.2255 0.00005
EFCAB1 79645 EF-hand calcium binding domain 1 −2.19918 0.00005
WNT8B 7479 Wingless-type MMTV integration site family, member 8B −2.19366 0.00005
PI15 51050 Peptidase inhibitor 15 −2.17615 0.00005
C1orf189 388701 Chromosome 1 open reading frame 189 −2.17531 0.01255
OLFML3 56944 Olfactomedin-like 3 −2.16835 0.0016