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Fig. 8 | Cell & Bioscience

Fig. 8

From: Restored expression of vitamin D receptor and sensitivity to 1,25-dihydroxyvitamin D3 in response to disrupted fusion FOP2FGFR1 gene in acute myeloid leukemia cells

Fig. 8

Differentiation of KG1 cells in response to curcumin and 1,25D. KG1 cells were exposed to 10 µM curcumin with or without 1,25D (10 or 100 nM) for 96 h and then the expression of CD11b and CD14 differentiation markers was detected using flow cytometry. Addition of 1,25D at both concentrations significantly enhanced the expression of CD14 in KG1 cells when compared to curcumin-treated cells. The experiments were repeated 5 times and illustrative dot-blots are presented in a, while the mean percentages of positive cells (±SEM) are presented in b. The samples that differ significantly from the curcumin-treated cells are marked with asterisk (p < 0.02)

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