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Fig. 7 | Cell & Bioscience

Fig. 7

From: Restored expression of vitamin D receptor and sensitivity to 1,25-dihydroxyvitamin D3 in response to disrupted fusion FOP2FGFR1 gene in acute myeloid leukemia cells

Fig. 7

Differentiation of KG1, KG1-CtrA and KG1-RARA cells in response to IFNs and 1,25D. KG1, KG1-CtrA and KG1-RARA cells were exposed to 10 ng/ml of IFNα, 10 ng/ml of IFNγ with or without 10 nM 1,25D for 96 h and then the expression of CD11b and CD14 differentiation markers was detected using flow cytometry. Experiments were repeated 3 (KG1 and KG1-RARA) or 4 (KG1-CtrA) times. The bar charts show the density of CD11b and CD14 antigens on the cell surface, expressed as mean channel of fluorescence (MCF) values (±SEM). Values that differ significantly (p < 0.05) from those obtained for 1,25D treated cells are marked with asterisks, while the values that differ significantly (p < 0.01) from those obtained for IFNγ-treated cells are marked by hash

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