Fig. 2

Inhibition of proliferation by gemcitabine. a Quantification of cell proliferation of 6606PDA, 6606l, and 7265PDA cells grown in media containing the indicated gemcitabine concentrations using WST-1 assays. b Comparison of EC50 values for each indicated cell line as measured by WST-1 assay. c Quantification of gemcitabine dependent cell proliferation of 6606PDA, 6606l, and 7265PDA cells using BrdU incorporation assays. d Presentation of EC50 values for each indicated cell line as measured by BrdU incorporation and comparison to published EC50 values from MIA PaCa-2 cells [13]. Significant differences (*P = 0.001) and a tendentious difference (^#P = 0.026) are shown in the box plots (number of independent experiments: n = 7 for 6606PDA; n = 8 for 6606l, n = 7 for 7265PDA in a and b; n = 7 for 6606PDA; n = 6 for 6606l, n = 6 in c and d)