Figure 9From: A 2-methoxyestradiol bis-sulphamoylated derivative induces apoptosis in breast cell linesEffects of EMBS on p53 expression. The protein expression of p53 was significantly increased when exposed to 0.4 μM for 24 h. The p53 protein expression of EMBS-treated MCF-7 cells were the most profoundly affected, followed by MCF-12A and MDA-MB-231 when compared to cells propagated in growth medium and vehicle-treated cells.Back to article page