Figure 5

Bar graph showing the average mean fluorescent intensity increase in the ESE-16-treated cells compared to the appropriate controls illustrating an increase in phosphatidylserine externalization. This bar graph represents the average MFI of all three repeats done. Cells propogated in medium had an average MFI of 11.31, the vehicle control had an average MFI of 15.74, the positive control had an average MFI of 18.82 while the ESE-16-treated cells an average MFI of 25.50. The increased MFI indicates an increase in PS externalization which is an early apoptotic indicator [35].