Clinicopathologic features | Peritumoral EpCAM density | P Value | Peritumral OV6 density | P Value | Peritumral CD133 density | P Value | Peritumral c-kit density | P Value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
High | Low | High | Low | High | Low | High | Low | |||||
Frequency (%) | 40 (33.3%) | 80 (66.7%) | Â | 34 (28.3%) | 86 (71.7%) | Â | 33 (27.5%) | 87 (72.5%) | Â | 39 (32.5%) | 81 (67.5%) | Â |
Gender | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Male | 35 | 73 | 0.747 | 30 | 78 | 0.946 | 30 | 78 | 1.000 | 37 | 71 | 0.363 |
Female | 5 | 7 | Â | 4 | 8 | Â | 3 | 9 | Â | 2 | 10 | Â |
Age | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤50 | 21 | 42 | 1.000 | 16 | 47 | 0.453 | 19 | 44 | 0.493 | 20 | 43 | 0.853 |
>50 | 19 | 38 | Â | 18 | 39 | Â | 14 | 43 | Â | 19 | 38 | Â |
AFP | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤400 | 25 | 56 | 0..408 | 22 | 59 | 0.681 | 23 | 58 | 0.752 | 24 | 57 | 0.333 |
>400 | 15 | 24 | Â | 12 | 27 | Â | 10 | 29 | Â | 15 | 24 | Â |
Cirrhosis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Absence | 20 | 51 | 0.149 | 19 | 52 | 0.645 | 17 | 54 | 0.294 | 17 | 54 | 0.016* |
Presence | 20 | 29 | Â | 15 | 34 | Â | 16 | 33 | Â | 22 | 27 | Â |
Satellite lesion | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Absence | 36 | 69 | 0.770 | 28 | 77 | 0.284 | 29 | 76 | 1.000 | 35 | 70 | 0.606 |
Presence | 4 | 11 | Â | 6 | 9 | Â | 4 | 11 | Â | 4 | 11 | Â |
Tumor size (cm) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤5cm | 15 | 37 | 0.362 | 15 | 37 | 0.913 | 16 | 36 | 0.483 | 18 | 34 | 0.665 |
>5cm | 25 | 43 | Â | 19 | 49 | Â | 17 | 51 | Â | 21 | 47 | Â |
Tumor encapsulation | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Absence | 26 | 61 | 0.193 | 26 | 61 | 0.540 | 23 | 64 | 0.672 | 27 | 60 | 0.578 |
Presence | 14 | 19 | Â | 8 | 25 | Â | 10 | 23 | Â | 12 | 21 | Â |
Microvascular invasion | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Absence | 17 | 38 | 0.604 | 17 | 38 | 0.565 | 18 | 37 | 0.238 | 22 | 33 | 0.107 |
Presence | 23 | 42 | Â | 17 | 48 | Â | 15 | 50 | Â | 17 | 48 | Â |
Major vascular invasion | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Absence | 39 | 75 | 0.657 | 33 | 81 | 0.853 | 29 | 85 | 0.083 | 38 | 76 | 0.687 |
Presence | 1 | 5 | Â | 1 | 5 | Â | 4 | 2 | Â | 1 | 5 | Â |
Edmondson grade | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Low (I/II) | 27 | 63 | 0.180 | 21 | 69 | 0.035* | 23 | 67 | 0.409 | 28 | 62 | 0.574 |
High (III/IV) | 13 | 17 | Â | 13 | 17 | Â | 10 | 20 | Â | 11 | 19 | Â |
TNM stage | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
I/II | 25 | 67 | 0.009* | 23 | 69 | 0.142 | 16 | 76 | <0.001* | 29 | 63 | 0.678 |
III | 15 | 13 | Â | 11 | 17 | Â | 17 | 11 | Â | 10 | 18 | Â |