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Figure 5 | Cell & Bioscience

Figure 5

From: Pinocembrin suppresses TGF-β1-induced epithelial-mesenchymal transition and metastasis of human Y-79 retinoblastoma cells through inactivating αvβ3 integrin/FAK/p38α signaling pathway

Figure 5

The inhibitory effect of pinocembrin on TGF-β1-induced phosphorylation of FAK/p38α in Y-79 cells. (A and B) Cells were pretreated with TGF-β1 (10 ng/ml) for 2 h and then incubated in 5 μ M pinocembrin for 0, 1, 2, 3, and 6 h. The total protein and phosphorylation levels of FAK (Tyr397, Tyr576, Tyr925), Smad2, JNK1/2, ERK1/2, p38α were measured by Western blotting. β-Actin was used as an internal control.

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Cell & Bioscience

ISSN: 2045-3701

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