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Table 3 Top differentially - expressed miRNAs with negative fold changes

From: Clinical biomarkers of pulmonary carcinoid tumors in never smokers via profiling miRNA and target mRNA

miRNA Bonferroni P-value (FF sample set) FDR (Q-value) (FF sample set) Fold change (FF sample set) Bonferroni P-value (FFPE sample set) FDR(Q-value) (FFPE sample set) Fold change (FFPE sample set)
miR-203 7.65E - 12 9.81E - 13 −5.27985 2.53E - 08 1.40E - 10 −3.47194
miR-224 3.35E - 09 4.77E - 11 −3.98143 6.67E - 07 3.26E - 09 −3.02567
miR-155 4.18E - 08 3.73E - 10 −3.79316 1.98E - 08 1.13E - 10 −3.00440
miR-302d 1 0.0280996 −2.07804 0.213123 0.000384031 −2.89387
miR-34b 6.04E - 05 2.53E - 07 −3.97282 0.0647553 0.000135572 −2.84861
miR-181b 6.15E - 11 4.54E - 12 −2.78165 2.56E - 10 2.06E - 12 −2.84466
miR-193a-5p 6.09E - 06 2.96E - 08 −2.47796 2.56E - 08 1.40E - 10 −2.82774
miR-34b* 0.202781 0.0003304 −2.35874 0.0239414 5.51E - 05 −2.68848
miR-222 6.14E - 09 7.38E - 11 −3.23244 0.0021736 6.33E - 06 −2.66284
miR-30a-3p 5.59E - 10 2.38E - 11 −3.68236 0.00758472 2.00E - 05 −2.65532
miR-938 1 0.032323 −2.11394 0.558499 0.000831352 −2.64146
miR-218 9.63E - 07 6.17E - 09 −3.60068 0.00014186 5.71E - 07 −2.54212
miR-511 6.18E - 10 2.38E - 11 −3.62032 2.35E - 05 1.01E - 07 −2.41325
miR-34c-3p 2.70E - 05 1.16E - 07 −3.12580 0.0165783 3.88E - 05 −2.37615
miR-10a 1.03E - 06 6.37E - 09 −3.11085 0.306927 0.000528712 −2.07425
miR-146a 5.81E - 06 2.87E - 08 −3.13742 0.0120827 2.95E - 05 −1.91491
miR-1 3.78E - 11 3.63E - 12 −3.16869 0.339905 0.000564228 −1.75322
  1. Note: We sorted miRNA on negative fold changes of FFPE and FF sample sets, respectively. We selected the top 12 in FF and FFPE of which the fold changes are denoted in italics, respectively. Seven miRNAs are the top 12 in both of the sample sets, and the other ten miRNAs are the top 12 in either of the sample sets. If the Bonferroni P-value or FDR (Q-value) are <0.05 or <0.01, they are labeled in bold font, respectively. Six miRNAs met all the criteria, i.e., Bonferroni P-value<0.05, FDR (Q-value)<0.01, and top fold changes in both sample sets are indicated by the deep shaded rows.
  2. FF=Fresh Frozen tissues.
  3. FFPE=Formalin-Fixed Paraffin-Embedded tissues.
  4. FDR=False Discovery Rate.