Comparison of antitumor effect induced by CRT/E6E7L2 DNA vaccination with electroporation. (A). Schematic illustration of the experiment. C57BL/6 mice were (6-12 mice/group) were challenged intravaginally with 2x104 TC-1 Luc cells. From day 7, mice were either left untreated or immunized with 10 μg/mouse of CRT/E6E7L2 DNA vaccine by intramuscular injection only or followed by electroporation. The mice were boosted twice with 3-day interval with the same regimen. (B) Tumor growth was followed every week by bioluminescence measurement (photons/sec/cm2). (C) Survival of the mice was monitored every other day.