Scorpion venom peptide SPVII promotes irradiated cells proliferation and increases the expression of the IL-3 receptor

Cell & Bioscience

Table 4 Effect of SVPII on irradiated M-NFS-60 cell cycle progression (% of total cells)

Group	G0-G1	G2-M	S	Apoptosis
Control	40.16 ± 3.40	6.69 ± 0.70	52.86 ± 4.83	0.01 ± 0.00
Irradiated	34.45 ± 1.75	31.71 ± 3.16	32.21 ± 2.65	15.81 ± 1.26
IL-310 μg/L	14.72 ± 0.91*	65.38 ± 5.11*	20.93 ± 2.76*	31.95 ± 4.11*
SVPII 3 mg/L	36.65 ± 2.07^#	46.27 ± 4.28*^#	16.92 ± 1.95*^#	21.09 ± 2.05*^#

Cells were unirradiated (Control), irradiated and then incubated for 48 h in media with 25% rhM-CSF (15.5 μg/L) for 48 h(Irradiated), or irradiated and then treated with 15.5 μg/L rhM-CSF + IL-3(IL-310 μg/L) or 15.5 μg/L rhM-CSF + SVPII(SVPII 3 mg/L). * P < 0.05 vs. irradiated group; ^#P < 0.05 vs. IL-310 μg/L group.