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Table 4 Effect of SVPII on irradiated M-NFS-60 cell cycle progression (% of total cells)

From: Scorpion venom peptide SPVII promotes irradiated cells proliferation and increases the expression of the IL-3 receptor

Group

G0-G1

G2-M

S

Apoptosis

Control

40.16 ± 3.40

6.69 ± 0.70

52.86 ± 4.83

0.01 ± 0.00

Irradiated

34.45 ± 1.75

31.71 ± 3.16

32.21 ± 2.65

15.81 ± 1.26

IL-310 μg/L

14.72 ± 0.91*

65.38 ± 5.11*

20.93 ± 2.76*

31.95 ± 4.11*

SVPII 3 mg/L

36.65 ± 2.07#

46.27 ± 4.28*#

16.92 ± 1.95*#

21.09 ± 2.05*#

  1. Cells were unirradiated (Control), irradiated and then incubated for 48 h in media with 25% rhM-CSF (15.5 μg/L) for 48 h(Irradiated), or irradiated and then treated with 15.5 μg/L rhM-CSF + IL-3(IL-310 μg/L) or 15.5 μg/L rhM-CSF + SVPII(SVPII 3 mg/L). * P < 0.05 vs. irradiated group; #P < 0.05 vs. IL-310 μg/L group.
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Cell & Bioscience

ISSN: 2045-3701

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