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Table 3 Univariate and multivariate analyses of various prognostic variables for recurrence-free survival in cohort 1

From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression

 

Univariate analysis

Multivariate analysis

 

P-value

Hazard ratio (95% CI)

P-value

Hazard ratio (95% CI)

Age

    

 ≤45

0.202

0.719 (0.433-1.193)

  

 >45

    

Menopausal status

0.768

0.915 (0.508-1.648)

  

Premenopausal

    

Postmenopausal

    

Tumor size (cm)

    

 ≤2

0.000

3.479 (1.881-6.435)

0.146

1.649(0.840-3.237)

 >2

Lymph node status

    

 Negative

<0.001

5.424 (2.932-10.036)

<0.001

4.205(2.205-8.017)

 Positive

ER

    

 Positive

0.012

0.519 (0.310-0.866)

0.060

0.606(0.359-1.021)

 Negative

PR

    

 Positive

0.020

0.528 (0.308-0.906)

  

 Negative

ErbB-2

    

 Positive

0.220

1.527 (0.777-3.004)

  

 Negative

MACC1 expression

    

 Positive

0.000

3.021 (1.659-5.501)

0.006

2.378(1.279-4.424)

 Negative