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Table 3 Univariate and multivariate analyses of various prognostic variables for recurrence-free survival in cohort 1

From: Overexpression of MACC1 and Its significance in human Breast Cancer Progression

  Univariate analysis Multivariate analysis
  P-value Hazard ratio (95% CI) P-value Hazard ratio (95% CI)
Age     
 ≤45 0.202 0.719 (0.433-1.193)   
 >45     
Menopausal status 0.768 0.915 (0.508-1.648)   
Premenopausal     
Postmenopausal     
Tumor size (cm)     
 ≤2 0.000 3.479 (1.881-6.435) 0.146 1.649(0.840-3.237)
 >2
Lymph node status     
 Negative <0.001 5.424 (2.932-10.036) <0.001 4.205(2.205-8.017)
 Positive
ER     
 Positive 0.012 0.519 (0.310-0.866) 0.060 0.606(0.359-1.021)
 Negative
PR     
 Positive 0.020 0.528 (0.308-0.906)   
 Negative
ErbB-2     
 Positive 0.220 1.527 (0.777-3.004)   
 Negative
MACC1 expression     
 Positive 0.000 3.021 (1.659-5.501) 0.006 2.378(1.279-4.424)
 Negative