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Table 2 A summary of the physiological function of nuclear hormone receptors in podocytes

From: Nuclear hormone receptors in podocytes

Nuclear receptor Role in kidney function/disease Reference
Estrogen receptor renoprotective blocks podocyte apoptosis [6164]
Glucocorticoid receptor well-known renoprotective functions of GR ligands [56, 6567]
Mineralocorticoid receptor renoprotective when suppressed [6874]
Peroxisome proliferator-activated receptor-α renoprotective enhances Nephrin expression [7578]
Peroxisome proliferator-activated receptor-γ renoprotective blocks podocyte apoptosis blocks podocyte hypertrophy/proliferation [7982]
Retinoic acid receptor-α renoprotective enhances podocyte differentiation [8390]
Vitamin D receptor reduces renal inflammation enhances Nephrin expression [9195]