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Table 5 Postnatal follow-up to verify the accuracy of prenatal ultrasound screening

From: Incidence, distribution, disease spectrum, and genetic deficits of congenital heart defects in China: implementation of prenatal ultrasound screening identified 18,171 affected fetuses from 2,452,249 pregnancies

Congenital heart defect

Postnatal agreement with prenatal screening

Postnatal disagreement with prenatal screening

Number of cases followed up

Agreement (%)

Postnatal imaging and surgery

VSD

738

98

836

88·28%

PLSVC

133

4

137

97·08%

ECD

115

10

125

92·00%

TOF

112

22

134

83·58%

CVR

104

4

108

96·30%

DORV

91

10

101

90·10%

TGA

54

4

58

93·10%

SV

49

11

60

81·67%

PS

44

12

56

78·57%

COA/IAA

20

24

44

45·45%

AS

42

7

49

85·71%

PTA

38

11

49

77·55%

PVS

32

0

32

100·00%

HS

17

0

17

100·00%

ASA

16

6

22

72·73%

Cardiac tumor

14

1

15

93·33%

HLHS

25

3

28

89·29%

EA

10

2

12

83·33%

Dextrocardia

10

0

10

100·00%

HRHS

9

0

9

100·00%

PA/VSD

7

0

7

100·00%

Dextrocardia

7

0

7

100·00%

TA

6

0

6

100·00%

Myocardiopathy

5

0

5

100·00%

DAS

5

0

5

100·00%

HRHS

4

1

5

80·00%

TVD

4

0

4

100·00%

TAPVD

3

1

4

75·00%

CAF

3

0

3

100·00%

CT

3

1

4

75·00%

MA

2

0

2

100·00%

PA

2

1

3

66·67%

AA

2

0

2

100·00%

DOLV

1

0

1

100·00%

PCDA

1

0

1

100·00%

PDA

1

0

1

100·00%

TVC

1

0

1

100·00%

NVM

0

1

1

0·00%

AVS

0

1

1

0·00%

Subtotal

1 = 730

235

1,965

88·04%

Autopsy of aborted fetus

VSD

621

53

674

92·14%

ECD

219

15

234

93·59%

TOF

153

21

174

87·93%

DORV

145

16

161

90·06%

TGA

111

9

120

92·50%

PTA

54

19

73

73·97%

PA

30

19

49

61·22%

COA/IAA

24

30

54

44·44%

SV

29

1

30

96·67%

Cardiac tumor

25

3

28

89·29%

HS

22

0

22

100·00%

HLHS

22

0

22

100·00%

HRHS

13

0

13

100·00%

Subtotal

1,468

186

1,654

88·75%

Total

3,198

421

3,619

88·37%

  1. AA = aortic atresia. AS = aortic stenosis. ASA = atrial septal aneurysm. AVS = aortic valve stenosis. CAF = coronary artery fistula. COA/IAA = coarctation of the aorta/interrupted aortic arch. CT = cor triatriatum. CVR = congenital vascular ring. DAS = ductus arteriosus stenosis. DOLV = double-outlet left ventricle. DORV = double-outlet right ventricle. EA = Ebstein's anomaly. ECD = endocardial cushion defect. HLHS = hypoplastic left heart syndrome. HRHS = hypoplastic right heart syndrome. HS = heterotaxy syndrome. MA = mitral atresia. NVM = noncompaction of the ventricular myocardium. PA = pulmonary atresia. PCDA = premature closure of the ductus arteriosus. PDA = patent ductus arteriosus. PLSVC = persistent left superior vena cava. PS = pulmonary stenosis. PTA = persistent truncus arteriosus. PVS = pulmonary vein stenosis. SV = single ventricle. TA = tricuspid atresia. TAPVD = total anomalous pulmonary venous drainage. TVC = tricuspid valve cleft. TVD = tricuspid valve dysplasia. TGA = transposition of the great arteries. TOF = tetralogy of Fallot. VSD = ventricular septal defect