Skip to main content


Page 30 of 30

  1. The TGFβ and Ras-MAPK pathways play critical roles in cell development and cell cycle regulation, as well as in tumor formation and metastasis. In the absence of cellular transformation, these pathways operate...

    Authors: Douglas A Chapnick, Lisa Warner, Jennifer Bernet, Timsi Rao and Xuedong Liu
    Citation: Cell & Bioscience 2011 1:42
  2. It remains unclear whether retroviruses can encode and express an intragenomic microRNA (miRNA). Some have suggested that processing by the Drosha and Dicer enzymes might preclude the viability of a replicatin...

    Authors: Zachary Klase, Laurent Houzet and Kuan-Teh Jeang
    Citation: Cell & Bioscience 2011 1:38
  3. Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat. It is held that in mammals, long-term surplus food inta...

    Authors: Xuan Yao, Shifang Shan, Ying Zhang and Hao Ying
    Citation: Cell & Bioscience 2011 1:35
  4. Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependenc...

    Authors: Xiuyun Jiang, Heidi L Kenerson and Raymond S Yeung
    Citation: Cell & Bioscience 2011 1:34
  5. Despite detailed in vivo knowledge of glycolytic enolases and many bacterial non-enolase members of the superfamily, little is known about the in vivo function of vertebrate non-enolase enolase superfamily member...

    Authors: Steve Finckbeiner, Pin-Joe Ko, Blake Carrington, Raman Sood, Kenneth Gross, Bruce Dolnick, Janice Sufrin and Paul Liu
    Citation: Cell & Bioscience 2011 1:32
  6. Adult organ-specific stem cells are essential for organ homeostasis and repair in adult vertebrates. The intestine is one of the best-studied organs in this regard. The intestinal epithelium undergoes constant...

    Authors: Yun-Bo Shi, Takashi Hasebe, Liezhen Fu, Kenta Fujimoto and Atsuko Ishizuya-Oka
    Citation: Cell & Bioscience 2011 1:30
  7. The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the body plan and also in the tumor invasion process. In addition, EMT also causes disruption of cell-cell adherence, loss...

    Authors: Yingying Jing, Zhipeng Han, Shanshan Zhang, Yan Liu and Lixin Wei
    Citation: Cell & Bioscience 2011 1:29
  8. Laribacter hongkongensis is a Gram-negative, sea gull-shaped rod associated with community-acquired gastroenteritis. The bacterium has been found in diverse freshwater environments including fish, frogs and drink...

    Authors: Susanna KP Lau, Rachel YY Fan, Gilman KM Wong, Jade LL Teng, Kong-Hung Sze, Herman Tse, Kwok-Yung Yuen and Patrick CY Woo
    Citation: Cell & Bioscience 2011 1:28
  9. Human papillomavirus (HPV) pseudovirions have recently been shown to deliver DNA efficiently in vivo, resulting in the priming of antigen-specific CD8+ T cells in vaccinated mice. In the current study, we compare...

    Authors: Shiwen Peng, Barbara Ma, Shu-Hsia Chen, Chien-Fu Hung and TC Wu
    Citation: Cell & Bioscience 2011 1:26
  10. The Inhibitor of Growth (ING) proteins represent a type II tumor suppressor family comprising five conserved genes, ING1 to ING5. While ING1, ING2 and ING3 proteins are stable components of the mSIN3a-HDAC comple...

    Authors: Susann Ludwig, Alexandra Klitzsch and Aria Baniahmad
    Citation: Cell & Bioscience 2011 1:25
  11. Thyroid hormone (TH) is involved in many biological functions such as animal development, cell differentiation, etc. Variation and/or disruption of plasma TH level often led to abnormalities and physiological ...

    Authors: Shao-Chung Hsia, Gautam R Bedadala and Matthew D Balish
    Citation: Cell & Bioscience 2011 1:24
  12. Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea and it can reside in human, fish, frogs and water. In this study, we performed an in-depth annotation of the ...

    Authors: Susanna KP Lau, Rachel YY Fan, Tom CC Ho, Gilman KM Wong, Alan KL Tsang, Jade LL Teng, Wenyang Chen, Rory M Watt, Shirly OT Curreem, Herman Tse, Kwok-Yung Yuen and Patrick CY Woo
    Citation: Cell & Bioscience 2011 1:22
  13. Hemorrhage increases inducible nitric oxide synthase (iNOS) and depletes ATP levels in various tissues. Previous studies have shown that geldanamycin, an inducer of heat shock protein 70kDa (HSP-70) and inhibi...

    Authors: Juliann G Kiang, Neil G Agravante, Joan T Smith and Phillip D Bowman
    Citation: Cell & Bioscience 2011 1:21
  14. Lithium, a drug that has long been used to treat bipolar disorder and some other human pathogenesis, has recently been shown to stimulate neural precursor growth. However, the involved mechanism is not clear. ...

    Authors: Zhaoxia Qu, Dongming Sun and Wise Young
    Citation: Cell & Bioscience 2011 1:18
  15. Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea. In this study, we performed an in-depth annotation of the genes in its genome related to the various steps i...

    Authors: Susanna KP Lau, Gilman KM Wong, Alan KL Tsang, Jade LL Teng, Rachel YY Fan, Herman Tse, Kwok-Yung Yuen and Patrick CY Woo
    Citation: Cell & Bioscience 2011 1:17
  16. Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea. In this study, we performed an in-depth annotation of the genes and pathways of the general metabolism of L....

    Authors: Shirly O Curreem, Jade L Teng, Herman Tse, Kwok-Yung Yuen, Susanna K Lau and Patrick C Woo
    Citation: Cell & Bioscience 2011 1:16
  17. This study describes the successful delivery of helper-dependent adenoviral vectors to the mouse retina with long term and robust levels of reporter expression in the retina without apparent adverse effects. S...

    Authors: Linda Wu, Simon Lam, Huibi Cao, Rui Guan, Rongqi Duan, Derek van der Kooy, Rod Bremner, Robert S Molday and Jim Hu
    Citation: Cell & Bioscience 2011 1:15
  18. Tissue inhibitor of metalloproteinase 1 (TIMP-1), which is thought to be produced mainly by activated hepatic stellate cells and Kupffer cells in the liver, plays a pivotal role in matrix remodeling during liv...

    Authors: Hua Wang, Fouad Lafdil, Lei Wang, Shi Yin, Dechun Feng and Bin Gao
    Citation: Cell & Bioscience 2011 1:14
  19. Breast cancer, the most common malignancy in women, still holds many secrets. The causes for non-hereditary breast cancer are still unknown. To elucidate any role for circulating naturally secreted proteins, a...

    Authors: Sofie C Van Huffel, Jill M Tham, XiaoQian Zhang, KohPang Lim, ChunXuan Yang, YikLoo Tan, Felicia Ong, Ian Lee and WanJin Hong
    Citation: Cell & Bioscience 2011 1:13
  20. Haloperidol is an antipsychotic drug that exerts its' antipsychotic effects by inhibiting dopaminergic neurons. Although the exact pathophysiology of haloperidol extrapyramidal symptoms are not known, the role...

    Authors: Joachim Perera, Joon Heng Tan, S Jeevathayaparan, Srikumar Chakravarthi and Nagaraja Haleagrahara
    Citation: Cell & Bioscience 2011 1:12
  21. During DNA replication or repair, disease-associated (CAG)n/(CTG)n expansion can result from formation of hairpin structures in the repeat tract of the newly synthesized or nicked DNA strand. Recent studies ident...

    Authors: Caixia Hou, Tianyi Zhang, Lei Tian, Jian Huang, Liya Gu and Guo-Min Li
    Citation: Cell & Bioscience 2011 1:11
  22. Age-related macular degeneration (AMD) is the leading cause of vision loss in elderly people over 60. The pathogenesis is still unclear. It has been suggested that lysosomal stress may lead to drusen formation...

    Authors: Patrick M Chen, Zoë J Gombart and Jeff W Chen
    Citation: Cell & Bioscience 2011 1:10
  23. Metastasis accounts for 90% of cancer-related mortality. Brain metastases generally present during the late stages in the natural history of cancer progression. Recent advances in cancer treatment and manageme...

    Authors: Chenyu Zhang and Dihua Yu
    Citation: Cell & Bioscience 2011 1:8
  24. Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the two major forms of primary liver cancers (PLC), accounting for approximately 90% and 5% respectively. The incidence of each is i...

    Authors: Mia Kumar, Xuelian Zhao and Xin Wei Wang
    Citation: Cell & Bioscience 2011 1:5
  25. MicroRNA (miRNA) molecules are potent mediators of post-transcriptional gene silencing that are emerging to be critical in the regulation of innate and adaptive immunity.

    Authors: Chih-Ping Mao, Liangmei He, Ya-Chea Tsai, Shiwen Peng, Tae Heung Kang, Xiaowu Pang, Archana Monie, Chien-Fu Hung and T-C Wu
    Citation: Cell & Bioscience 2011 1:3
  26. This Editorial briefly introduces the Society of Chinese Bioscientists in America (SCBA) to readers of Cell & Bioscience.

    Authors: Kuan-Teh Jeang
    Citation: Cell & Bioscience 2011 1:2