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  1. CRISPR and CRISPR-associated (Cas) protein, as components of microbial adaptive immune system, allows biologists to edit genomic DNA in a precise and specific way. CRISPR-Cas systems are classified into two ma...

    Authors: Fatemeh Safari, Khadijeh Zare, Manica Negahdaripour, Mazyar Barekati-Mowahed and Younes Ghasemi

    Citation: Cell & Bioscience 2019 9:36

    Content type: Review

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  2. Human mannose binding lectin (MBL) and dendritic cell-associated C-type lectin-1 (Dectin-1) are the two prototypical PRRs of innate immunity, whose direct role in recurrent vulvovaginal infections (RVVI) defen...

    Authors: Namarta Kalia, Jatinder Singh, Sujata Sharma and Manpreet Kaur

    Citation: Cell & Bioscience 2019 9:35

    Content type: Research

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  3. Previous studies have shown that in myogenic precursors, the homeoprotein Msx1 and its protein partners, histone methyltransferases and repressive histone marks, tend to be enriched on target myogenic regulato...

    Authors: Zhangjing Ma, Huiyuan Shi, Yi Shen, Huixia Li, Yu Yang, Jiange Yang, Hui Zhao, Gang Wang and Jingqiang Wang

    Citation: Cell & Bioscience 2019 9:34

    Content type: Research

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  5. Physical exercise is well known to benefit human health at every age. However, the exact mechanism through which physical exercise improves health remains unknown. Recent studies into exercise-induced myokine ...

    Authors: Xin Zhou, MengMeng Xu, Joseph L. Bryant, Jianjie Ma and Xuehong Xu

    Citation: Cell & Bioscience 2019 9:32

    Content type: Research highlight

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  6. Pyroptosis, a type of programmed cell death that along with inflammation, is mainly regulated by two main pathways, cysteinyl aspartate specific proteinase (caspase)-1-induced canonical inflammatory pathway an...

    Authors: Xiaoli Huang, Yang Feng, Guanqing Xiong, Shona Whyte, Jing Duan, Yucen Yang, Kaiyu Wang, Shiyong Yang, Yi Geng, Yangping Ou and Defang Chen

    Citation: Cell & Bioscience 2019 9:31

    Content type: Review

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  7. Cancer stem cells obtain energy demand through the activation of glycolysis and lipolysis. It seems that the use of approached targeting glycolysis and lipolysis could be an effective strategy for the inhibiti...

    Authors: Ayda Pouyafar, Milad Zadi Heydarabad, Jalal Abdolalizadeh, Reza Rahbarghazi and Mehdi Talebi

    Citation: Cell & Bioscience 2019 9:30

    Content type: Letter to the Editor

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    The Correction to this article has been published in Cell & Bioscience 2019 9:37

  8. Although the β-carboline alkaloids harman and norharman are considered as plant metabolites, they can also be secreted by fungi such as the entomopathogen Conidiobolus coronatus. Norharman and harman are also kno...

    Authors: Anna Katarzyna Wrońska and Mieczysława Irena Boguś

    Citation: Cell & Bioscience 2019 9:29

    Content type: Research

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  9. Small nucleolar RNA host gene 7 (SNHG7) is a novel identified oncogenic gene in tumorigenesis. However, the role that SNHG7 plays in pancreatic cancer (PC) remains unclear. In this study, we aimed to investiga...

    Authors: Dongfeng Cheng, Juanjuan Fan, Yang Ma, Yiran Zhou, Kai Qin, Minmin Shi and Jingrui Yang

    Citation: Cell & Bioscience 2019 9:28

    Content type: Research

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  10. Mitochondria are energy factories of cells and are important pivots for intracellular interactions with other organelles. They interact with the endoplasmic reticulum, peroxisomes, and nucleus through signal t...

    Authors: MengFang Xia, YaZhuo Zhang, Ke Jin, ZiTong Lu, Zhaoyang Zeng and Wei Xiong

    Citation: Cell & Bioscience 2019 9:27

    Content type: Review

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  11. As the main player in humoral immunity, antibodies play indispensable roles in the body’s immune system. Plasma cells (PCs), as antibody factories, are important contributors to humoral immunity. PCs, recogniz...

    Authors: Xue Wang, Gui-liang Hao, Bo-ya Wang, Chen-chen Gao, Yue-xiu Wang, Li-sheng Li and Jing-dong Xu

    Citation: Cell & Bioscience 2019 9:26

    Content type: Review

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  12. The range of radiation threats we face today includes everything from individual radiation exposures to mass casualties resulting from a terrorist incident, and many of these exposure scenarios include the lik...

    Authors: Juliann G. Kiang and Ayodele O. Olabisi

    Citation: Cell & Bioscience 2019 9:25

    Content type: Review

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  14. Portal vein tumor thrombosis (PVTT) in hepatocellular carcinoma (HCC) is a sign of advanced stage disease, which is associated with poor prognosis. Liver resection (LR) may provide better prognosis in selected...

    Authors: Lei Huo, Wenxin Wei, Zhenlin Yan, Zhengqing Lei, Yanting Xie, Renyan Gong, Shengyu Huang, Ningyang Jia and Yong Xia

    Citation: Cell & Bioscience 2019 9:23

    Content type: Research

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  15. Liver cancer is one of the major causes of cancer death worldwide, with significantly higher incidence and mortality among the male patients. Although sex hormones and their receptors could contribute to such ...

    Authors: Tatsuo Kido and Yun-Fai Chris Lau

    Citation: Cell & Bioscience 2019 9:22

    Content type: Research

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  16. Dexamethasone (Dex) are widely used for the treatment of asthma. However, they may cause apoptosis of bronchial epithelial cells and delay the recovery of asthma. Therefore, it is an urgent problem to find eff...

    Authors: Wenjing Zou, Chao Niu, Zhou Fu and Caihui Gong

    Citation: Cell & Bioscience 2019 9:18

    Content type: Research

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  17. Zinc finger 644 (Zfp644 in mouse, ZNF644 in human) gene is a transcription factor whose mutation S672G is considered a potential genetic factor of inherited high myopia. ZNF644 interacts with G9a/GLP complex, ...

    Authors: Katarzyna I. Szczerkowska, Silvia Petrezselyova, Jiri Lindovsky, Marcela Palkova, Jan Dvorak, Peter Makovicky, Mingyan Fang, Chongyi Jiang, Lingyan Chen, Mingming Shi, Xiao Liu, Jianguo Zhang, Agnieszka Kubik-Zahorodna, Bjoern Schuster, Inken M. Beck, Vendula Novosadova…

    Citation: Cell & Bioscience 2019 9:21

    Content type: Research

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  18. Endothelial cells (EC) are sensitive to changes in the microenvironment, including hypoxia and ischemia. Disruption of the microtubular network has been reported in cases of ischemia. However, the signaling pa...

    Authors: Huaming Cao, Dongsheng Yu, Xueyun Yan, Bing Wang, Zhiming Yu, Yu Song and Liang Sheng

    Citation: Cell & Bioscience 2019 9:20

    Content type: Research

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  19. Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of multivesicular bodies and the plasma membrane. They were shown to carry cell-specific cargos of proteins, lipids, and ge...

    Authors: Yuan Zhang, Yunfeng Liu, Haiying Liu and Wai Ho Tang

    Citation: Cell & Bioscience 2019 9:19

    Content type: Review

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  20. Mesenchymal stem cells (MSCs) have been extensively explored as a promising therapeutic agent in the field of bone tissue engineering due to their osteogenic differentiation ability. In this study, the osteoge...

    Authors: Chongyang Shen, Chuan Yang, Shijun Xu and Hai Zhao

    Citation: Cell & Bioscience 2019 9:17

    Content type: Research

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  21. Neoadjuvant chemotherapy (NAC) induces a pathological complete response (pCR) in ~ 30% of patients with breast cancer. However, aberrant DNA methylation alterations are frequent events during breast cancer pro...

    Authors: Yumei Luo, Juan Huang, Yi Tang, Xitu Luo, Lingxia Ge, Xiujie Sheng, Xiaofang Sun, Yaoyong Chen and Detu Zhu

    Citation: Cell & Bioscience 2019 9:16

    Content type: Research

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  22. More than the two decades, the question of whether vitamin D has a role in cancer frequency, development, and death has been premeditated in detail. Colorectal, breast, and prostate cancers have been a scrupul...

    Authors: Suhail Razak, Tayyaba Afsar, Ali Almajwal, Iftikhar Alam and Sarwat Jahan

    Citation: Cell & Bioscience 2019 9:15

    Content type: Research

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  23. Breast cancer was dangerous to women health. A growing number of evidences indicate that long non-coding RNAs (lncRNAs) have many functions in the development and progression of breast cancer and may serve as ...

    Authors: Xiaopeng Hu, Yun Liu, Yaying Du, Teng Cheng and Wenfei Xia

    Citation: Cell & Bioscience 2019 9:14

    Content type: Research

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  24. Psychological and physical stress can either enhance or suppress immune functions depending on a variety of factors such as duration and severity of stressful situation. Chronic stress exerts a significantly s...

    Authors: Anna Qin, Ting Zhong, Huajiao Zou, Xiaoya Wan, Bifeng Yao, Xinbin Zheng and Deling Yin

    Citation: Cell & Bioscience 2019 9:13

    Content type: Research

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  25. Proliferative vitreoretinopathy (PVR) is a severe blinding complication of retinal detachment surgery. Increasing evidence demonstrate that PVR is associated with oxidative stress. Scutellarin is a natural fla...

    Authors: Xin Hu, Xiaofang Wu, Bo Zhao and Yongyi Wang

    Citation: Cell & Bioscience 2019 9:12

    Content type: Research

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  26. The aim of this study was to investigate the role of long non-coding RNAs (LncRNAs) antisense non-coding RNA in the INK4 locus (ANRIL) in anti-inflammation of rhein in uric acid nephropathy (UAN) rats.

    Authors: Jiacai Hu, Daochun Wang, Hao Wu, Zhijie Yang, Na Yang and Junjun Dong

    Citation: Cell & Bioscience 2019 9:11

    Content type: Research

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  28. Transmembrane protein 108 (Tmem108) is a risk gene of psychiatric diseases including schizophrenia, bipolar disorder and major depression disorder. However, the pathophysiological mechanisms of Tmem108 are lar...

    Authors: Zheng Yu, Dong Lin, Yanzi Zhong, Bin Luo, Shengsheng Liu, Erkang Fei, Xinsheng Lai, Suqi Zou and Shunqi Wang

    Citation: Cell & Bioscience 2019 9:9

    Content type: Research

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  29. Calcium signaling are conserved from invertebrates to vertebrates and plays critical roles in many molecular mechanisms of embryogenesis and postnatal development. As a critical component of the signaling path...

    Authors: Rui Feng, Xin Zhou, Wei Zhang, Tao Pu, Yuting Sun, Rong Yang, Dan Wang, Xiaofei Zhang, Yingfeng Gao, Zhenlu Cai, Yu Liang, Qiuxia Yu, Yajun Wu, Xinjuan Lei, Zhijia Liang, Odell Jones…

    Citation: Cell & Bioscience 2019 9:8

    Content type: Research

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  30. Cellular senescence is a major hurdle for primary cell-based tissue engineering and regenerative medicine. Telomere erosion, oxidative stress, the expression of oncogenes and the loss of tumor suppressor genes...

    Authors: Yiming Wang, Song Chen, Zuoqin Yan and Ming Pei

    Citation: Cell & Bioscience 2019 9:7

    Content type: Review

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  32. TRAF3 is known as a central mediator of type I interferon (IFN) induction by various pattern recognition receptors, but the in vivo function of TRAF3 in host defense against viral infection is poorly defined d...

    Authors: Xiaoping Xie, Jin Jin, Lele Zhu, Zuliang Jie, Yanchuan Li, Baoyu Zhao, Xuhong Cheng, Pingwei Li and Shao-Cong Sun

    Citation: Cell & Bioscience 2019 9:5

    Content type: Research

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  33. Cancer patients treated with chemotherapy often experience a rapid decline of blood neutrophils, a dose-limiting side effect called chemotherapy-induced neutropenia. This complication brings about dose reducti...

    Authors: Jinseon Jeong, Yong-Jae Kim, Do Young Lee, Byoung-Gon Moon, Ki-Young Sohn, Sun Young Yoon and Jae Wha Kim

    Citation: Cell & Bioscience 2019 9:4

    Content type: Research

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  34. The PI3K/Akt and the STAT3 pathways are functionally associated in many tumor types. Both in vitro and in vivo studies have revealed that either biochemical or genetic manipulation of the STAT3 pathway activit...

    Authors: María Elisa Picco, María Victoria Castro, María Josefina Quezada, Gastón Barbero, María Belén Villanueva, Natalia Brenda Fernández, Hyungsoo Kim and Pablo Lopez-Bergami

    Citation: Cell & Bioscience 2019 9:3

    Content type: Research

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  36. To determine whether and how exosomes from human umbilical vein endothelial cells (HUVEC-Exos) regulates vascular smooth muscle cells (VSMCs) calcification/senescence in high glucose condition.

    Authors: Shuang Li, Jun-Kun Zhan, Yan-Jiao Wang, Xiao Lin, Jia-Yu Zhong, Yi Wang, Pan Tan, Jie-Yu He, Xing-Jun Cui, Yi-Yin Chen, Wu Huang and You-Shuo Liu

    Citation: Cell & Bioscience 2019 9:1

    Content type: Research

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  37. Sialic acids represent common terminal residues on numerous mammalian glycoconjugates, thereby influencing e.g. lumen formation in developing blood vessels. Interestingly, besides monosialylated also polysialy...

    Authors: Sebastian Strubl, Uwe Schubert, Andrea Kühnle, Alexander Rebl, Negah Ahmadvand, Silvia Fischer, Klaus T. Preissner and Sebastian P. Galuska

    Citation: Cell & Bioscience 2018 8:64

    Content type: Research

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  38. Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate gene or protein expression; however, their function in the progression of hepatic fibrosis remains unclear. Hepatic fibrosis is a cont...

    Authors: Hu Peng, Lin-Yan Wan, Jia-Jie Liang, Yan-Qiong Zhang, Wen-Bing Ai and Jiang-Feng Wu

    Citation: Cell & Bioscience 2018 8:63

    Content type: Review

    Published on:

  39. Evaluating the risk category of gastrointestinal stromal tumors (GISTs) is crucial for predicting prognosis and choosing treatment strategies, and tumor metastasis usually represent poor prognosis. Tumor necro...

    Authors: Zequn Li, Wei Zhang, Yi Li, Shougen Cao, Shanglong Liu, Liang Ning, Xuelong Jiao, Zimin Liu, Xiaoming Xing, Yujun Li and Yanbing Zhou

    Citation: Cell & Bioscience 2018 8:62

    Content type: Research

    Published on:

  40. Increasing evidence has suggested the involvement of long non-coding RNA taurine upregulated gene 1 (TUG1) in chemoresistance of cancer treatment. However, its function and molecular mechanisms in esophageal s...

    Authors: Caihui Xu, Yinmou Guo, Haiyan Liu, Gongbin Chen, Yanju Yan and Teng Liu

    Citation: Cell & Bioscience 2018 8:61

    Content type: Research

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  41. Microglia activation is a crucial event in neurodegenerative disease. The depression of microglial inflammatory response is considered a promising therapeutic strategy. NFκB signaling, including IKK/IκB phosph...

    Authors: Huanhuan Wang, Wenhai Huang, Meihao Liang, Yingying Shi, Chixiao Zhang, Qin Li, Meng Liu, Yikai Shou, Hongping Yin, Xiaozheng Zhu, Xiaoyan Sun, Yu Hu and Zhengrong Shen

    Citation: Cell & Bioscience 2018 8:60

    Content type: Research

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  44. It has been reported that CBP/p300-Interacting Transactivator with glutamic acid [E]/aspartic acid [D]-rich C-terminal domain 1 (CITED1) is overexpressed in papillary thyroid cancer (PTC). However, the functio...

    Authors: Hai Li, Hongyu Guan, Yan Guo, Weiwei Liang, Liehua Liu, Xiaoying He, Weijian Ke, Xiaopei Cao, Haipeng Xiao and Yanbing Li

    Citation: Cell & Bioscience 2018 8:57

    Content type: Research

    Published on:

  45. Contrary to Warburg’s hypothesis, mitochondrial oxidative phosphorylation (OXPHOS) contributes significantly to fueling cancer cells. Several recent studies have demonstrated that radiotherapy-resistant and ch...

    Authors: Sarada Preeta Kalainayakan, Keely E. FitzGerald, Purna Chaitanya Konduri, Chantal Vidal and Li Zhang

    Citation: Cell & Bioscience 2018 8:56

    Content type: Review

    Published on:

  46. Fine osseointegration is the basis of long-term survival of implant. In our previous study, we observed a strong correlation between hyperlipidemia and compromised osseointegration. MicroRNA-29a-3p (miR-29a-3p...

    Authors: Fei Liu, Zhifeng Wang, Fangfang Liu, Jinzhao Xu, Qibo Liu, Kaifeng Yin and Jing Lan

    Citation: Cell & Bioscience 2018 8:55

    Content type: Research

    Published on:

  49. Mycobacterium smegmatis, a rapidly growing non-tuberculosis mycobacterium, is a good model for studying the pathogenesis of tuberculosis because of its genetic similarity to Mycobacterium tuberculosis (Mtb). Macr...

    Authors: Seon-Hwa Kim, Soo-Na Cho, Yun-Ji Lim, Ji-Ae Choi, Junghwan Lee, Dam Go and Chang-Hwa Song

    Citation: Cell & Bioscience 2018 8:52

    Content type: Research

    Published on:

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Cell & Bioscience

ISSN: 2045-3701

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