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Fig. 4 | Cell & Bioscience

Fig. 4

From: Modulating AHR function offers exciting therapeutic potential in gut immunity and inflammation

Fig. 4

Schematic represents the effects of AHR on gut immunity and inflammation in intestinal mucosal immune system. Activation of AHR plays an important role in regulating intestinal immunity (on left). the deficiency of AHR results in intestinal inflammation (on right). ILCs, innate lymphoid cells; IELs, intraepithelial lymphocytes; IECs, intestinal epithelial cells; AHR, aryl hydrocarbon receptor; ROR γt + , RORγt + ILCs; Notch1, tight junction protein Notch1; ZO-1, tight junction proteins zonula occludens-1

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