Fig. 3From: Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats Single-cell RNA sequencing identified distinct proximal tubular populations in the kidneys of rats. A Heatmap of novel marker genes of subpopulations in proximal tubular. B, CÂ UMAP snRNA-seq and spatial feature plots of marker genes expressed by proximal tubular subpopulations. D Violin plots of selected markers expression in distinct injured-proximal tubular cells. The representative immunohistochemistry images were adopted from the Human Protein Atlas (https://www.proteinatlas.org/). E Left: Spp1 and Havcr1 expression feature plots generated via ST platform; Right: Violin plots of Spp1 and Havcr1 in the kidney of calculi ratsBack to article page