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Fig. 2 | Cell & Bioscience

Fig. 2

From: Identification and validation of CCL2 as a potential biomarker relevant to mast cell infiltration in the testicular immune microenvironment of spermatogenic dysfunction

Fig. 2

Identification of hub immune genes related to both spermatogenesis and testicular mast cell infiltration (discovery set). A and B Venn diagrams of DEGs, immune genes intersecting with genes in blue module or turquoise module, respectively. The de-duplicated immune genes list was from ImmPort dataset. C PPI network of potential hub immune genes selected by top 10 MCC values. Color intensity of boxes changed positively with the increasing of MCC value. DM Expression patterns of 10 potential hub genes in testicular microenvironment. Red color deepened with the expression value of a certain gene. PPI, protein–protein interaction. MCC, maximum clique centrality

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