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Fig. 3 | Cell & Bioscience

Fig. 3

From: Meloxicam inhibits STING phosphorylation and alleviates intracellular DNA-mediated autoimmune responses

Fig. 3

MXC does not inhibit cGAS activation. a, b Mass spectroscopy analysis of cGAMP production of L929 cells (a) and U937 (b) cells treated with 0.5 µg/ml HT-DNA for 3 h following a 6 h of pretreatment with 500 µM MXC. ND, not detected. c, d qPCR analysis of interferon-beta mRNA expression in L929 cells (c) and U937 cells (d) treated with 1 µg/ml cGAMP for 1 h following a 6 h of pretreatment with 500 µM MXC. NT, untreated. ND, not detected. Data are presented as the mean ± s.e.m. *P < 0.05, ***P < 0.001. Data represent at least three biological independent experiments

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Cell & Bioscience

ISSN: 2045-3701

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