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Fig. 4 | Cell & Bioscience

Fig. 4

From: Impacts of plasma microbial lipopolysaccharide translocation on B cell perturbations and anti-CD4 autoantibody production in people with HIV on suppressive antiretroviral therapy

Fig. 4

LPS promotes IgG class switch recombination in vitro. B cells were isolated from C57BL/6J mice and cultured with medium, LPS (3 µg/mL) plus IL-4 (5 ng/mL), IFN-γ (50 ng/mL), or TGF-β1 (2 ng/mL) for 96 h. Shown are the representative dot plots and summarized percentages of proliferating IgG subclass B cells in total B cells (%CFSElowIgG1/2a/2b/IgG3 + in B220 + cells). Non-parametric Mann-Whitney tests were used to analyze data

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Cell & Bioscience

ISSN: 2045-3701

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